Compile Data Set for Download or QSAR
maximum 50k data
Found 23 of ic50 data for polymerid = 50004796
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM525152(Ms-QFR-kbt | N-0385 | US10988505, Example 2)
Affinity DataIC50:  1.90nMAssay Description:Vero E6 cells were transfected with mock (pcDNA3.1), TMPRSS2 (pcDNA3.1/TMPRSS2 Uniprot: O15393-1), or TMPRSS2-S441A (pcDNA3.1/TMPRSS2-S441A) using Li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50032698(CHEMBL3354676 | N-0130)
Affinity DataIC50:  3.10nMAssay Description:Vero E6 cells were transfected with mock (pcDNA3.1), TMPRSS2 (pcDNA3.1/TMPRSS2 Uniprot: O15393-1), or TMPRSS2-S441A (pcDNA3.1/TMPRSS2-S441A) using Li...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM525153(Ac-QFR-kbt | N-0386 | US10988505, Example 3)
Affinity DataIC50:  3.90nMAssay Description:Vero E6 cells were transfected with mock (pcDNA3.1), TMPRSS2 (pcDNA3.1/TMPRSS2 Uniprot: O15393-1), or TMPRSS2-S441A (pcDNA3.1/TMPRSS2-S441A) using Li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM525256((H)Arg-Glu-Phe-Arg-kbt | N-0438)
Affinity DataIC50:  5.20nMAssay Description:Vero E6 cells were transfected with mock (pcDNA3.1), TMPRSS2 (pcDNA3.1/TMPRSS2 Uniprot: O15393-1), or TMPRSS2-S441A (pcDNA3.1/TMPRSS2-S441A) using Li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50031706(4-Guanidino-benzoic acid 4-dimethylcarbamoylmethox...)
Affinity DataIC50:  18nMAssay Description:Vero E6 cells were transfected with mock (pcDNA3.1), TMPRSS2 (pcDNA3.1/TMPRSS2 Uniprot: O15393-1), or TMPRSS2-S441A (pcDNA3.1/TMPRSS2-S441A) using Li...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50239965(Bromhexine | CHEBI:77032)
Affinity DataIC50:  750nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM420291(0591-5329 | 4-(Methoxycarbonyl)phenyl thiophene-2-...)
Affinity DataIC50:  930nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM45440(4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of TMPRSS2 (247 to 492 residues) (unknown origin) peptidase domain expressed in Escherichia coli BL21 (DE3) incubated for 30 mins followed...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50022172((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid meth...)
Affinity DataIC50:  1.37E+3nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM420294(8008-1235 | N-[4-(4-chlorophenyl)-3-ethyl-1,3-thia...)
Affinity DataIC50:  2.64E+3nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM420292(4401-0077 | Antidepressant agent 1)
Affinity DataIC50:  2.68E+3nMAssay Description:To identify inhibitors of TMPRSS2 that may be used directly in clinical studies or as lead compounds to develop targeted drugs, we screened several c...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50613302(CHEMBL5285196)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of TMPRSS2 (106 to 492 residues) (unknown origin) using Boc-QAR-AMC as substrate measured for 20 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50613298(CHEMBL5270157)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of TMPRSS2 (106 to 492 residues) (unknown origin) using Boc-QAR-AMC as substrate measured for 20 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50613303(CHEMBL5266850)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of TMPRSS2 (106 to 492 residues) (unknown origin) using Boc-QAR-AMC as substrate measured for 20 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50368092(GNF-PF-3839 | PROPAMIDINE CHLORIDE)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of TMPRSS2 (247 to 492 residues) (unknown origin) peptidase domain expressed in Escherichia coli BL21 (DE3) incubated for 30 mins followed...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50613299(CHEMBL5271456)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of TMPRSS2 (106 to 492 residues) (unknown origin) using Boc-QAR-AMC as substrate measured for 20 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM525259(Ms-Gln-Phe-Arg-kbt(OH) | N-0385(OH))
Affinity DataIC50: >1.00E+4nMAssay Description:Vero E6 cells were transfected with mock (pcDNA3.1), TMPRSS2 (pcDNA3.1/TMPRSS2 Uniprot: O15393-1), or TMPRSS2-S441A (pcDNA3.1/TMPRSS2-S441A) using Li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50613305(CHEMBL5287275)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of TMPRSS2 (106 to 492 residues) (unknown origin) using Boc-QAR-AMC as substrate measured for 20 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50613300(CHEMBL5275059)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of TMPRSS2 (106 to 492 residues) (unknown origin) using Boc-QAR-AMC as substrate measured for 20 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50613301(CHEMBL5270536)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of TMPRSS2 (106 to 492 residues) (unknown origin) using Boc-QAR-AMC as substrate measured for 20 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50613304(CHEMBL5275526)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of TMPRSS2 (106 to 492 residues) (unknown origin) using Boc-QAR-AMC as substrate measured for 20 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50122613(3,4-dihydroisoquinoline-2(1H)-carboximidamide | CH...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of TMPRSS2 (106 to 492 residues) (unknown origin) using Boc-QAR-AMC as substrate measured for 20 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTransmembrane protease serine 2(Homo sapiens (Human))
University of British Columbia

LigandPNGBDBM50122613(3,4-dihydroisoquinoline-2(1H)-carboximidamide | CH...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of TMPRSS2 (247 to 492 residues) (unknown origin) peptidase domain expressed in Escherichia coli BL21 (DE3) incubated for 30 mins followed...More data for this Ligand-Target Pair
In DepthDetails PubMed